Dag1 Company Profile

Aggregated data from the web about Dag1

Company Name	Dag1
Website	https://ghr.nlm.nih.gov
Snippet	Apr 16, 2019 · The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
End	108,263,958 bp[2]
PDB	Ortholog search: PDBe RCSB
Band	9 F1\|9 59.08 cM
Chr.	Chromosome 9 (mouse)[2]
Entrez	1605
Aliases	DAG1, 156DAG, A3a, AGRNR, DAG, MDDGC7, MDDGC9, MDDGA9, dystroglycan 1, LGMDR16
Country	netherlands
Ensembl	ENSG00000173402
Founded	2012.0
Species	Human
UniProt	Q14118
Website	dag1.nl
Industry	staffing and recruiting
linkedin	linkedin.com/company/dag1
size_range	51 - 200
display_url	dag1.nl
External IDs	OMIM: 128239 MGI: 101864 HomoloGene: 3234 GeneCards: DAG1
Headquarters	utrecht, utrecht, netherlands
Gene ontology	Gene ontologyMolecular function• calcium ion binding• protein binding• virus receptor activity• alpha-actinin binding• vinculin binding• actin binding• tubulin binding• structural constituent of muscle• SH2 domain binding• laminin binding• laminin-1 binding• dystroglycan bindingCellular component• cell-cell junction• cell-cell adherens junction• cell nucleus• synapse• contractile ring• filopodium• node of Ranvier• costamere• lamellipodium• dystroglycan complex• membrane raft• cell junction• cytoskeleton• membrane• extracellular exosome• basolateral plasma membrane• postsynaptic membrane• sarcolemma• cytoplasm• integral component of membrane• focal adhesion• plasma membrane• dystrophin-associated glycoprotein complex• nucleoplasm• basement membrane• cytosol• extracellular space• endoplasmic reticulum lumen• Golgi lumen• plasma membrane raft• external side of plasma membrane• nuclear periphery• extracellular matrix• extracellular region• collagen-containing extracellular matrix• glutamatergic synapse• GABA-ergic synapse• postsynaptic cytosolBiological process• NLS-bearing protein import into nucleus• extracellular matrix organization• viral process• regulation of embryonic cell shape• response to peptide hormone• regulation of epithelial to mesenchymal transition• positive regulation of basement membrane assembly involved in embryonic body morphogenesis• Viral entry• regulation of gastrulation• cytoskeletal anchoring at plasma membrane• negative regulation of cell migration• Schwann cell development• membrane protein ectodomain proteolysis• calcium-dependent cell-matrix adhesion• negative regulation of MAPK cascade• nerve maturation• microtubule anchoring• commissural neuron axon guidance• branching involved in salivary gland morphogenesis• negative regulation of protein kinase B signaling• morphogenesis of an epithelial sheet• myelination in peripheral nervous system• basement membrane organization• epithelial tube branching involved in lung morphogenesis• modulation by virus of host morphology or physiology• protein O-linked glycosylation• positive regulation of cell-matrix adhesion• aging• Schwann cell differentiation• response to denervation involved in regulation of muscle adaptation• nerve development• axon regeneration• positive regulation of myelination• skeletal muscle tissue regeneration• positive regulation of protein kinase activity• positive regulation of oligodendrocyte differentiation• cellular response to mechanical stimulus• cellular response to cholesterol• angiogenesis involved in wound healing• regulation of synapse organization• regulation of neurotransmitter receptor localization to postsynaptic specialization membrane• retrograde trans-synaptic signaling by trans-synaptic protein complexSources:Amigo / QuickGO
PubMed search	[3]
RefSeq (mRNA)	NM_004393NM_001165928NM_001177634NM_001177635NM_001177636NM_001177637NM_001177638NM_001177639NM_001177640NM_001177641NM_001177642NM_001177643NM_001177644
Location (UCSC)	Chr 3: 49.47 – 49.54 Mb
RefSeq (protein)	NP_001159400NP_001171105NP_001171106NP_001171107NP_001171108NP_001171109NP_001171110NP_001171111NP_001171112NP_001171113NP_001171114NP_001171115NP_004384
Biological process	• NLS-bearing protein import into nucleus• extracellular matrix organization• viral process• regulation of embryonic cell shape• response to peptide hormone• regulation of epithelial to mesenchymal transition• positive regulation of basement membrane assembly involved in embryonic body morphogenesis• Viral entry• regulation of gastrulation• cytoskeletal anchoring at plasma membrane• negative regulation of cell migration• Schwann cell development• membrane protein ectodomain proteolysis• calcium-dependent cell-matrix adhesion• negative regulation of MAPK cascade• nerve maturation• microtubule anchoring• commissural neuron axon guidance• branching involved in salivary gland morphogenesis• negative regulation of protein kinase B signaling• morphogenesis of an epithelial sheet• myelination in peripheral nervous system• basement membrane organization• epithelial tube branching involved in lung morphogenesis• modulation by virus of host morphology or physiology• protein O-linked glycosylation• positive regulation of cell-matrix adhesion• aging• Schwann cell differentiation• response to denervation involved in regulation of muscle adaptation• nerve development• axon regeneration• positive regulation of myelination• skeletal muscle tissue regeneration• positive regulation of protein kinase activity• positive regulation of oligodendrocyte differentiation• cellular response to mechanical stimulus• cellular response to cholesterol• angiogenesis involved in wound healing• regulation of synapse organization• regulation of neurotransmitter receptor localization to postsynaptic specialization membrane• retrograde trans-synaptic signaling by trans-synaptic protein complex
Cellular component	• cell-cell junction• cell-cell adherens junction• cell nucleus• synapse• contractile ring• filopodium• node of Ranvier• costamere• lamellipodium• dystroglycan complex• membrane raft• cell junction• cytoskeleton• membrane• extracellular exosome• basolateral plasma membrane• postsynaptic membrane• sarcolemma• cytoplasm• integral component of membrane• focal adhesion• plasma membrane• dystrophin-associated glycoprotein complex• nucleoplasm• basement membrane• cytosol• extracellular space• endoplasmic reticulum lumen• Golgi lumen• plasma membrane raft• external side of plasma membrane• nuclear periphery• extracellular matrix• extracellular region• collagen-containing extracellular matrix• glutamatergic synapse• GABA-ergic synapse• postsynaptic cytosol
Molecular function	• calcium ion binding• protein binding• virus receptor activity• alpha-actinin binding• vinculin binding• actin binding• tubulin binding• structural constituent of muscle• SH2 domain binding• laminin binding• laminin-1 binding• dystroglycan binding
Number of employees	24
Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EG4, 2MK7
List of PDB id codes	List of PDB id codes1EG4, 2MK7
Gene location (Human)	Gene location (Human)Chr.Chromosome 3 (human)[1]Band3p21.31Start49,468,703 bp[1]End49,535,618 bp[1]
Gene location (Mouse)	Gene location (Mouse)Chr.Chromosome 9 (mouse)[2]Band9 F1\|9 59.08 cMStart108,204,634 bp[2]End108,263,958 bp[2]
RNA expression pattern	RNA expression patternMore reference expression data

Have a list of company names and need to update information? Use our Company Search tool.

Please note that Powrbot Inc does not own this content and cannot vouch for its accuracy, we simply aggregate public information for ease of research.

Want to update this profile? Please contact us here with a link to the public source verifying the edit.