Company Name | Dolex |
---|---|
Website | https://www.dolex.com |
Snippet | The verification code entered did not match the code sent to your phone. |
KEGG | D00217 Y, C06804 |
UNII | 362O9ITL9D |
ChEBI | CHEBI:46195 Y |
ChEMBL | ChEMBL112 Y |
Country | united states |
Density | 1.263 g/cm3 |
Formula | C8H9NO2 |
Website | dolex.fr |
ATC code | N02BE01 (WHO) N02BE51 (WHO) N02BE71 (WHO) |
DrugBank | DB00316 Y |
Industry | consumer electronics |
linkedin.com/company/dolex-inc | |
Excretion | Urine (85–90%)[3] |
CAS Number | 103-90-2 Y |
ChemSpider | 1906 Y |
Drug class | Analgesics and antipyretics |
IUPHAR/BPS | 5239 |
Metabolism | Predominantly in the liver[3] |
Molar mass | 151.163 g·mol−1 |
PDB ligand | TYL (PDBe, RCSB PDB) |
size_range | 1 - 10 |
MedlinePlus | a681004 |
Metabolites | APAP gluc, APAP sulfate, APAP GSH, APAP cys, NAPQI[6] |
Other names | N-acetyl-para-aminophenol (APAP), acetaminophen (USAN US) |
PubChem CID | 1983 |
PubChem SID | 46506142 |
Trade names | Tylenol, Panadol, others[2] |
display_url | dolex.fr |
Headquarters | chamblee, georgia, united states |
Legal status | AU: S4 (Rx), OTC, and unscheduled, UK: General sales list (GSL, OTC), US: OTC / Rx-only |
License data | US DailyMed: Acetaminophen, US FDA: Acetaminophen |
Boiling point | 420 °C (788 °F) |
ECHA InfoCard | 100.002.870 |
Melting point | 169 °C (336 °F) [10][11] |
Pronunciation | Paracetamol: /ˌpærəˈsiːtəmɒl/Acetaminophen: /əˌsiːtəˈmɪnəfɪn/ (listen) |
AHFS/Drugs.com | Monograph |
Bioavailability | 63–89%[4]:73 |
Onset of action | Pain relief onset by route:By mouth – 37 minutes[7]Buccal – 15 minutes[7]Intravenous – 8 minutes[7] |
Protein binding | 10–25%[5] |
3D model (JSmol) | Interactive image |
Pregnancycategory | AU: A [1], US: N (Not classified yet) [1], |
Solubility in water | 7.21 g/kg (0 °C)[9], 8.21 g/kg (5 °C)[9], 9.44 g/kg (10 °C)[9], 10.97 g/kg (15 °C)[9], 12.78 g/kg (20 °C)[9], ~14 mg/ml (20 °C) |
Elimination half-life | 2–2.5 hours[8] |
CompTox Dashboard (EPA) | DTXSID2020006 |
Routes ofadministration | By mouth, through the cheek, rectal, intravenous (IV) |
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