Dolex Company Profile

Aggregated data from the web about Dolex
Company Name Dolex
Website https://www.dolex.com
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KEGG D00217 Y, C06804
UNII 362O9ITL9D
ChEBI CHEBI:46195 Y
ChEMBL ChEMBL112 Y
Country united states
Density 1.263 g/cm3
Formula C8H9NO2
Website dolex.fr
ATC code N02BE01 (WHO) N02BE51 (WHO) N02BE71 (WHO)
DrugBank DB00316 Y
Industry consumer electronics
linkedin linkedin.com/company/dolex-inc
Excretion Urine (85–90%)[3]
CAS Number 103-90-2 Y
ChemSpider 1906 Y
Drug class Analgesics and antipyretics
IUPHAR/BPS 5239
Metabolism Predominantly in the liver[3]
Molar mass 151.163 g·mol−1
PDB ligand TYL (PDBe, RCSB PDB)
size_range 1 - 10
MedlinePlus a681004
Metabolites APAP gluc, APAP sulfate, APAP GSH, APAP cys, NAPQI[6]
Other names N-acetyl-para-aminophenol (APAP), acetaminophen (USAN US)
PubChem CID 1983
PubChem SID 46506142
Trade names Tylenol, Panadol, others[2]
display_url dolex.fr
Headquarters chamblee, georgia, united states
Legal status AU: S4 (Rx), OTC, and unscheduled, UK: General sales list (GSL, OTC), US: OTC / Rx-only
License data US DailyMed: Acetaminophen, US FDA: Acetaminophen
Boiling point 420 °C (788 °F)
ECHA InfoCard 100.002.870
Melting point 169 °C (336 °F) [10][11]
Pronunciation Paracetamol: /ˌpærəˈsiːtəmɒl/Acetaminophen: /əˌsiːtəˈmɪnəfɪn/ (listen)
AHFS/Drugs.com Monograph
Bioavailability 63–89%[4]:73
Onset of action Pain relief onset by route:By mouth – 37 minutes[7]Buccal – 15 minutes[7]Intravenous – 8 minutes[7]
Protein binding 10–25%[5]
3D model (JSmol) Interactive image
Pregnancycategory AU: A [1], US: N (Not classified yet) [1],
Solubility in water 7.21 g/kg (0 °C)[9], 8.21 g/kg (5 °C)[9], 9.44 g/kg (10 °C)[9], 10.97 g/kg (15 °C)[9], 12.78 g/kg (20 °C)[9], ~14 mg/ml (20 °C)
Elimination half-life 2–2.5 hours[8]
CompTox Dashboard (EPA) DTXSID2020006
Routes ofadministration By mouth, through the cheek, rectal, intravenous (IV)

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