Rela Company Profile

Aggregated data from the web about Rela

Company Name	Rela
Website	https://www.relainstitute.com
Snippet	Dr Rela Institute and Medical Centre, an International Medical facility, is a quaternary care hospital committed to being an internationally significant health care system with the state-of-the art treatment facilities designed to deliver healthcare at an affordable cost. RIMC, Chennai is one of the world’s largest dedicated liver intensive care units with world-renowned doctors who are ...
End	5,648,130 bp[2]
PDB	Ortholog search: PDBe RCSB
Band	19 A\|19 4.34 cM
Chr.	Chromosome 19 (mouse)[2]
Entrez	5970
Aliases	RELA, NFKB3, p65, RELA proto-oncogene, NF-kB subunit, CMCU
Ensembl	ENSG00000173039
Species	Human
UniProt	Q04206
External IDs	OMIM: 164014 MGI: 103290 HomoloGene: 32064 GeneCards: RELA
Gene ontology	Gene ontologyMolecular function• protein N-terminus binding• ankyrin repeat binding• GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific• histone deacetylase binding• repressing transcription factor binding• activating transcription factor binding• enzyme binding• phosphate ion binding• GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding• protein homodimerization activity• chromatin binding• NF-kappaB binding• GO:0001948 protein binding• protein kinase binding• DNA binding• sequence-specific DNA binding• actinin binding• protein heterodimerization activity• transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding• chromatin DNA binding• ubiquitin protein ligase binding• GO:0000983 RNA polymerase II general transcription initiation factor activity• RNA polymerase II regulatory region sequence-specific DNA binding• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity• GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific• identical protein binding• GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific• transcription factor binding• GO:0032403 macromolecular complex binding• RNA polymerase II transcription coactivator bindingCellular component• cytoplasm• cytosol• I-kappaB/NF-kappaB complex• transcription regulator complex• NF-kappaB complex• nucleoplasm• nuclear chromatin• cell nucleus• nucleolus• NF-kappaB p50/p65 complex• macromolecular complex• synapse• glutamatergic synapseBiological process• response to amino acid• response to interleukin-1• cellular response to interleukin-6• response to progesterone• response to organic substance• Fc-epsilon receptor signaling pathway• negative regulation of insulin receptor signaling pathway• defense response to virus• positive regulation of chondrocyte differentiation• animal organ morphogenesis• response to muscle stretch• response to cytokine• negative regulation of protein catabolic process• cytokine-mediated signaling pathway• negative regulation of extrinsic apoptotic signaling pathway• response to mechanical stimulus• response to muramyl dipeptide• stimulatory C-type lectin receptor signaling pathway• transcription, DNA-templated• response to insulin• negative regulation of NIK/NF-kappaB signaling• nucleotide-binding oligomerization domain containing 2 signaling pathway• membrane protein intracellular domain proteolysis• inflammatory response• GO:0022415 viral process• response to cobalamin• hair follicle development• positive regulation of miRNA metabolic process• acetaldehyde metabolic process• cellular response to hepatocyte growth factor stimulus• cellular response to nicotine• negative regulation of apoptotic process• cellular defense response• response to morphine• response to lipopolysaccharide• cellular response to interleukin-1• response to inorganic substance• regulation of inflammatory response• response to cAMP• negative regulation of transcription, DNA-templated• response to hydrogen peroxide• positive regulation of Schwann cell differentiation• defense response• response to bacterium• response to organic cyclic compound• aging• positive regulation of cell proliferation• positive regulation of I-kappaB kinase/NF-kappaB signaling• liver development• response to UV-B• T cell receptor signaling pathway• cellular response to lipopolysaccharide• positive regulation of type I interferon production• response to drug• positive regulation of transcription from RNA polymerase II promoter• cellular response to hydrogen peroxide• regulation of transcription, DNA-templated• tumor necrosis factor-mediated signaling pathway• positive regulation of transcription, DNA-templated• positive regulation of T cell receptor signaling pathway• positive regulation of NF-kappaB transcription factor activity• cellular response to peptidoglycan• cellular response to tumor necrosis factor• regulation of NIK/NF-kappaB signaling• positive regulation of NIK/NF-kappaB signaling• positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus• positive regulation of pri-miRNA transcription from RNA polymerase II promoter• regulation of DNA-templated transcription in response to stress• cellular response to lipoteichoic acid• negative regulation of transcription from RNA polymerase II promoter• negative regulation of protein sumoylation• pri-miRNA transcription from RNA polymerase II promoter• cellular response to angiotensin• interleukin-1-mediated signaling pathway• cellular response to vascular endothelial growth factor stimulus• negative regulation of pri-miRNA transcription from RNA polymerase II promoter• postsynapse to nucleus signaling pathway• chromatin organization• I-kappaB kinase/NF-kappaB signaling• NIK/NF-kappaB signaling• positive regulation of leukocyte adhesion to vascular endothelial cellSources:Amigo / QuickGO
PubMed search	[3]
RefSeq (mRNA)	NM_001145138NM_001243984NM_001243985NM_021975
Location (UCSC)	Chr 11: 65.65 – 65.66 Mb
RefSeq (protein)	NP_001138610NP_001230913NP_001230914NP_068810
Biological process	• response to amino acid• response to interleukin-1• cellular response to interleukin-6• response to progesterone• response to organic substance• Fc-epsilon receptor signaling pathway• negative regulation of insulin receptor signaling pathway• defense response to virus• positive regulation of chondrocyte differentiation• animal organ morphogenesis• response to muscle stretch• response to cytokine• negative regulation of protein catabolic process• cytokine-mediated signaling pathway• negative regulation of extrinsic apoptotic signaling pathway• response to mechanical stimulus• response to muramyl dipeptide• stimulatory C-type lectin receptor signaling pathway• transcription, DNA-templated• response to insulin• negative regulation of NIK/NF-kappaB signaling• nucleotide-binding oligomerization domain containing 2 signaling pathway• membrane protein intracellular domain proteolysis• inflammatory response• GO:0022415 viral process• response to cobalamin• hair follicle development• positive regulation of miRNA metabolic process• acetaldehyde metabolic process• cellular response to hepatocyte growth factor stimulus• cellular response to nicotine• negative regulation of apoptotic process• cellular defense response• response to morphine• response to lipopolysaccharide• cellular response to interleukin-1• response to inorganic substance• regulation of inflammatory response• response to cAMP• negative regulation of transcription, DNA-templated• response to hydrogen peroxide• positive regulation of Schwann cell differentiation• defense response• response to bacterium• response to organic cyclic compound• aging• positive regulation of cell proliferation• positive regulation of I-kappaB kinase/NF-kappaB signaling• liver development• response to UV-B• T cell receptor signaling pathway• cellular response to lipopolysaccharide• positive regulation of type I interferon production• response to drug• positive regulation of transcription from RNA polymerase II promoter• cellular response to hydrogen peroxide• regulation of transcription, DNA-templated• tumor necrosis factor-mediated signaling pathway• positive regulation of transcription, DNA-templated• positive regulation of T cell receptor signaling pathway• positive regulation of NF-kappaB transcription factor activity• cellular response to peptidoglycan• cellular response to tumor necrosis factor• regulation of NIK/NF-kappaB signaling• positive regulation of NIK/NF-kappaB signaling• positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus• positive regulation of pri-miRNA transcription from RNA polymerase II promoter• regulation of DNA-templated transcription in response to stress• cellular response to lipoteichoic acid• negative regulation of transcription from RNA polymerase II promoter• negative regulation of protein sumoylation• pri-miRNA transcription from RNA polymerase II promoter• cellular response to angiotensin• interleukin-1-mediated signaling pathway• cellular response to vascular endothelial growth factor stimulus• negative regulation of pri-miRNA transcription from RNA polymerase II promoter• postsynapse to nucleus signaling pathway• chromatin organization• I-kappaB kinase/NF-kappaB signaling• NIK/NF-kappaB signaling• positive regulation of leukocyte adhesion to vascular endothelial cell
Cellular component	• cytoplasm• cytosol• I-kappaB/NF-kappaB complex• transcription regulator complex• NF-kappaB complex• nucleoplasm• nuclear chromatin• cell nucleus• nucleolus• NF-kappaB p50/p65 complex• macromolecular complex• synapse• glutamatergic synapse
Molecular function	• protein N-terminus binding• ankyrin repeat binding• GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific• histone deacetylase binding• repressing transcription factor binding• activating transcription factor binding• enzyme binding• phosphate ion binding• GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding• protein homodimerization activity• chromatin binding• NF-kappaB binding• GO:0001948 protein binding• protein kinase binding• DNA binding• sequence-specific DNA binding• actinin binding• protein heterodimerization activity• transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding• chromatin DNA binding• ubiquitin protein ligase binding• GO:0000983 RNA polymerase II general transcription initiation factor activity• RNA polymerase II regulatory region sequence-specific DNA binding• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity• GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific• identical protein binding• GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific• transcription factor binding• GO:0032403 macromolecular complex binding• RNA polymerase II transcription coactivator binding
Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4KV4, 1NFI, 2LSP, 2O61, 3GUT, 3QXY, 3RC0, 4KV1, 2N22
List of PDB id codes	List of PDB id codes4KV4, 1NFI, 2LSP, 2O61, 3GUT, 3QXY, 3RC0, 4KV1, 2N22
Gene location (Human)	Gene location (Human)Chr.Chromosome 11 (human)[1]Band11q13.1Start65,653,597 bp[1]End65,663,090 bp[1]
Gene location (Mouse)	Gene location (Mouse)Chr.Chromosome 19 (mouse)[2]Band19 A\|19 4.34 cMStart5,637,483 bp[2]End5,648,130 bp[2]
RNA expression pattern	RNA expression patternMore reference expression data

Have a list of company names and need to update information? Use our Company Search tool.

Please note that Powrbot Inc does not own this content and cannot vouch for its accuracy, we simply aggregate public information for ease of research.

Want to update this profile? Please contact us here with a link to the public source verifying the edit.